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Molecular Insights into Determinants of Translational Readthrough and Implications for Nonsense Suppression Approaches
The fidelity of protein synthesis, a process shaped by several mechanisms involving specialized ribosome regions and external factors, ensures the precise reading of sense and stop codons. However, premature termination codons (PTCs) arising from mutations may, at low frequency, be misrecognized and...
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| Udgivet i: | Int J Mol Sci |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
MDPI
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7764779/ https://ncbi.nlm.nih.gov/pubmed/33322589 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21249449 |
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