NOTCH1 Signaling in Head and Neck Squamous Cell Carcinoma

Biomarker-driven targeted therapies are lacking for head and neck squamous cell carcinoma (HNSCC), which is common and lethal. Efforts to develop such therapies are hindered by a genomic landscape dominated by the loss of tumor suppressor function, including NOTCH1 that is frequently mutated in HNSC...

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Dettagli Bibliografici
Pubblicato in:Cells
Autori principali: Shah, Pooja A., Huang, Chenfei, Li, Qiuli, Kazi, Sawad A., Byers, Lauren A., Wang, Jing, Johnson, Faye M., Frederick, Mitchell J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2020
Soggetti:
Review
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7764697/
https://ncbi.nlm.nih.gov/pubmed/33322834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9122677
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