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The NOTCH Pathway in Head and Neck Squamous Cell Carcinoma

Comprehensive genomic analyses have been performed for head and neck squamous cell carcinoma (HNSCC), revealing a significant rate of NOTCH1 mutations and identifying NOTCH1 as the second most frequently mutated gene after TP53. Most NOTCH1 mutations are considered inactivating, indicating that NOTC...

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Detalhes bibliográficos
Publicado no:J Dent Res
Main Authors: Fukusumi, T., Califano, J.A.
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5960881/
https://ncbi.nlm.nih.gov/pubmed/29489439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0022034518760297
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