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Drug–Drug Interactions Involving Intestinal and Hepatic CYP1A Enzymes

Cytochrome P450 (CYP) 1A enzymes are considerably expressed in the human intestine and liver and involved in the biotransformation of about 10% of marketed drugs. Despite this doubtless clinical relevance, CYP1A1 and CYP1A2 are still somewhat underestimated in terms of unwanted side effects and drug...

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Publicado en:Pharmaceutics
Main Authors: Klomp, Florian, Wenzel, Christoph, Drozdzik, Marek, Oswald, Stefan
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7764576/
https://ncbi.nlm.nih.gov/pubmed/33322313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics12121201
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