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Organic Cation Transporter 1 an Intestinal Uptake Transporter: Fact or Fiction?

Intestinal transporter proteins are known to affect the pharmacokinetics and in turn the efficacy and safety of many orally administered drugs in a clinically relevant manner. This knowledge is especially well-established for intestinal ATP-binding cassette transporters such as P-gp and BCRP. In con...

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Bibliographic Details
Published in:Front Pharmacol
Main Authors: Wenzel, Christoph, Drozdzik, Marek, Oswald, Stefan
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2021
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8080103/
https://ncbi.nlm.nih.gov/pubmed/33935750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.648388
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