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Mass Spectrometry-Based Targeted Proteomics as a Tool to Elucidate the Expression and Function of Intestinal Drug Transporters

Intestinal transporter proteins affect the oral bioavailability of many drugs in a significant manner. In order to estimate or predict their impact on oral drug absorption, data on their intestinal expression levels are needed. So far, predominantly mRNA expression data are available which are not n...

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Detalhes bibliográficos
Main Authors: Oswald, Stefan, Gröer, Christian, Drozdzik, Marek, Siegmund, Werner
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3787215/
https://ncbi.nlm.nih.gov/pubmed/23982336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-013-9521-3
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