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Mass Spectrometry-Based Targeted Proteomics as a Tool to Elucidate the Expression and Function of Intestinal Drug Transporters

Intestinal transporter proteins affect the oral bioavailability of many drugs in a significant manner. In order to estimate or predict their impact on oral drug absorption, data on their intestinal expression levels are needed. So far, predominantly mRNA expression data are available which are not n...

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Autors principals: Oswald, Stefan, Gröer, Christian, Drozdzik, Marek, Siegmund, Werner
Format: Artigo
Idioma:Inglês
Publicat: Springer US 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3787215/
https://ncbi.nlm.nih.gov/pubmed/23982336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-013-9521-3
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