Data-driven prioritization and preclinical evaluation of therapeutic targets in glioblastoma

BACKGROUND: Patients with glioblastoma (GBM) have a dismal prognosis, and there is an unmet need for new therapeutic options. This study aims to identify new therapeutic targets in GBM. METHODS: mRNA expression data of patient-derived GBM (n = 1279) and normal brain tissue (n = 46) samples were coll...

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Bibliografiska uppgifter
I publikationen:Neurooncol Adv
Huvudupphovsmän: Brahm, Cyrillo G, Abdul, U Kulsoom, Houweling, Megan, van Linde, Myra E, Lagerweij, Tonny, Verheul, Henk M W, Westerman, Bart A, Walenkamp, Annemiek M E, Fehrmann, Rudolf S N
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2020
Ämnen:
Basic and Translational Investigations
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7764503/
https://ncbi.nlm.nih.gov/pubmed/33392504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/noajnl/vdaa151
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