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The Molecular ‘Myc-anisms’ Behind Myc-Driven Tumorigenesis and the Relevant Myc-Directed Therapeutics

MYC, a well-studied proto-oncogene that is overexpressed in >20% of tumors across all cancers, is classically known as “undruggable” due to its crucial roles in cell processes and its lack of a drug binding pocket. Four decades of research and creativity led to the discovery of a myriad of indire...

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Bibliografiske detaljer
Udgivet i:Int J Mol Sci
Main Authors: McAnulty, Jessica, DiFeo, Analisa
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7764474/
https://ncbi.nlm.nih.gov/pubmed/33322239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21249486
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