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Glycosaminoglycan Modification of Decorin Depends on MMP14 Activity and Regulates Collagen Assembly

Proper processing of collagens COL1 and COL6 is required for normal function of adipose tissue and skeletal muscle. Proteoglycan decorin (DCN) regulates collagen fiber formation. The amino-terminus of DCN is modified with an O-linked glycosaminoglycan (GAG), the function of which has remained unclea...

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Publicat a:Cells
Autors principals: Daquinag, Alexes C., Gao, Zhanguo, Fussell, Cale, Sun, Kai, Kolonin, Mikhail G.
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7764107/
https://ncbi.nlm.nih.gov/pubmed/33317052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9122646
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