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PDGFRα/PDGFRβ signaling balance modulates progenitor cell differentiation into white and beige adipocytes

The relative abundance of thermogenic beige adipocytes and lipid-storing white adipocytes in adipose tissue underlie its metabolic activity. The roles of adipocyte progenitor cells, which express PDGFRα or PDGFRβ, in adipose tissue function have remained unclear. Here, by defining the developmental...

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Detalhes bibliográficos
Publicado no:Development
Main Authors: Gao, Zhanguo, Daquinag, Alexes C., Su, Fei, Snyder, Brad, Kolonin, Mikhail G.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6514402/
https://ncbi.nlm.nih.gov/pubmed/29158445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.155861
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