Retinoic acid induces white adipose tissue browning by increasing adipose vascularity and inducing beige adipogenesis of PDGFRα(+) adipose progenitors

Formation of beige adipocytes within white adipose tissue enhances energy expenditure, which is a promising strategy to reduce obesity and prevent metabolic symptoms. Vitamin A and its bioactive metabolite, retinoic acid (RA), have regulatory roles in lipid metabolism. Here we report that RA induces...

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Vydáno v:Cell Discov
Hlavní autoři: Wang, Bo, Fu, Xing, Liang, Xingwei, Deavila, Jeanene M, Wang, Zhixiu, Zhao, Liang, Tian, Qiyu, Zhao, Junxing, Gomez, Noe Alberto, Trombetta, Sophie C, Zhu, Mei-Jun, Du, Min
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5633810/
https://ncbi.nlm.nih.gov/pubmed/29021914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/celldisc.2017.36
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