Effects of Different Drug Combinations in Immunodeficient Mice Infected with an Influenza A/H3N2 Virus

The prolonged treatment of immunosuppressed (IS) individuals with anti-influenza monotherapies may lead to the emergence of drug-resistant variants. Herein, we evaluated oseltamivir and polymerase inhibitors combinations against influenza A/H3N2 infections in an IS mouse model. Mice were IS with cyc...

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Veröffentlicht in:Microorganisms
Hauptverfasser: Mhamdi, Zeineb, Fausther-Bovendo, Hugues, Uyar, Olus, Carbonneau, Julie, Venable, Marie-Christine, Abed, Yacine, Kobinger, Gary, Boivin, Guy, Baz, Mariana
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7764069/
https://ncbi.nlm.nih.gov/pubmed/33322333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/microorganisms8121968
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