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Effects of Different Drug Combinations in Immunodeficient Mice Infected with an Influenza A/H3N2 Virus

The prolonged treatment of immunosuppressed (IS) individuals with anti-influenza monotherapies may lead to the emergence of drug-resistant variants. Herein, we evaluated oseltamivir and polymerase inhibitors combinations against influenza A/H3N2 infections in an IS mouse model. Mice were IS with cyc...

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Detalhes bibliográficos
Publicado no:Microorganisms
Main Authors: Mhamdi, Zeineb, Fausther-Bovendo, Hugues, Uyar, Olus, Carbonneau, Julie, Venable, Marie-Christine, Abed, Yacine, Kobinger, Gary, Boivin, Guy, Baz, Mariana
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7764069/
https://ncbi.nlm.nih.gov/pubmed/33322333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/microorganisms8121968
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