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Combination Therapy with Oseltamivir and Favipiravir Delays Mortality but Does Not Prevent Oseltamivir Resistance in Immunodeficient Mice Infected with Pandemic A(H1N1) Influenza Virus

Immunosuppressed individuals can shed influenza virus for prolonged periods of time, leading to the frequent emergence of antiviral resistance. We evaluated the benefits of oseltamivir and favipiravir combination therapy compared to single antiviral agents and monitored the emergence of drug-resista...

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Detalhes bibliográficos
Publicado no:Viruses
Main Authors: Baz, Mariana, Carbonneau, Julie, Rhéaume, Chantal, Cavanagh, Marie-Hélène, Boivin, Guy
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6266789/
https://ncbi.nlm.nih.gov/pubmed/30400276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v10110610
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