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Combination Therapy with Oseltamivir and Favipiravir Delays Mortality but Does Not Prevent Oseltamivir Resistance in Immunodeficient Mice Infected with Pandemic A(H1N1) Influenza Virus

Immunosuppressed individuals can shed influenza virus for prolonged periods of time, leading to the frequent emergence of antiviral resistance. We evaluated the benefits of oseltamivir and favipiravir combination therapy compared to single antiviral agents and monitored the emergence of drug-resista...

詳細記述

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書誌詳細
出版年:Viruses
主要な著者: Baz, Mariana, Carbonneau, Julie, Rhéaume, Chantal, Cavanagh, Marie-Hélène, Boivin, Guy
フォーマット: Artigo
言語:Inglês
出版事項: MDPI 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6266789/
https://ncbi.nlm.nih.gov/pubmed/30400276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v10110610
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