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Synergistic PA and HA mutations confer mouse adaptation of a contemporary A/H3N2 influenza virus

The mouse is the most widely used animal model for influenza virus research. However, the susceptibility of mice to seasonal influenza virus depends on the strain of mouse and on the strain of the influenza virus. Seasonal A/H3N2 influenza viruses do not replicate well in mice and therefore they nee...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Baz, Mariana, M’hamdi, Zeineb, Carbonneau, Julie, Lavigne, Sophie, Couture, Christian, Abed, Yacine, Boivin, Guy
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6851088/
https://ncbi.nlm.nih.gov/pubmed/31719554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-51877-4
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