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RNA-Seq Analysis of Cisplatin and the Monofunctional Platinum(II) Complex, Phenanthriplatin, in A549 Non-Small Cell Lung Cancer and IMR90 Lung Fibroblast Cell Lines

Phenanthriplatin is a new monofunctional platinum(II) complex that binds only one strand of DNA and acts by blocking gene transcription, but its effect on gene regulation has not been characterized relative to the traditional platinum-based complex, cisplatin. A549 non-small cell lung cancer and IMR...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Monroe, Jerry D., Moolani, Satya A., Irihamye, Elvin N., Speed, Joshua S., Gibert, Yann, Smith, Michael E.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7764052/
https://ncbi.nlm.nih.gov/pubmed/33302475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9122637
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