Dichloroacetate Radiosensitizes Hypoxic Breast Cancer Cells

Mitochondrial metabolism is an attractive target for cancer therapy. Reprogramming metabolic pathways can potentially sensitize tumors with limited treatment options, such as triple-negative breast cancer (TNBC), to chemo- and/or radiotherapy. Dichloroacetate (DCA) is a specific inhibitor of the pyr...

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Bibliografiske detaljer
Udgivet i:Int J Mol Sci
Main Authors: de Mey, Sven, Dufait, Inès, Jiang, Heng, Corbet, Cyril, Wang, Hui, Van De Gucht, Melissa, Kerkhove, Lisa, Law, Ka Lun, Vandenplas, Hugo, Gevaert, Thierry, Feron, Olivier, De Ridder, Mark
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7763818/
https://ncbi.nlm.nih.gov/pubmed/33316932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21249367
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