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Dichloroacetate Radiosensitizes Hypoxic Breast Cancer Cells
Mitochondrial metabolism is an attractive target for cancer therapy. Reprogramming metabolic pathways can potentially sensitize tumors with limited treatment options, such as triple-negative breast cancer (TNBC), to chemo- and/or radiotherapy. Dichloroacetate (DCA) is a specific inhibitor of the pyr...
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| Publicado en: | Int J Mol Sci |
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| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
MDPI
2020
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7763818/ https://ncbi.nlm.nih.gov/pubmed/33316932 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21249367 |
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