Distinct Immunoglobulin Fc Glycosylation Patterns Are Associated with Disease Nonprogression and Broadly Neutralizing Antibody Responses in Children with HIV Infection

A prophylactic HIV vaccine would ideally induce protective immunity prior to sexual debut. Children develop broadly neutralizing antibody (bnAb) responses faster and at higher frequencies than adults, but little is known about the underlying mechanisms or the potential role of Fc-mediated effector f...

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Detalhes bibliográficos
Publicado no:mSphere
Main Authors: Muenchhoff, M., Chung, A. W., Roider, J., Dugast, Anne-Sophie, Richardson, Simone, Kløverpris, Henrik, Leslie, Alasdair, Ndung’u, Thumbi, Moore, Penny, Alter, Galit, Goulder, Philip J. R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7763548/
https://ncbi.nlm.nih.gov/pubmed/33361123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mSphere.00880-20
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