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Distinct Immunoglobulin Fc Glycosylation Patterns Are Associated with Disease Nonprogression and Broadly Neutralizing Antibody Responses in Children with HIV Infection

A prophylactic HIV vaccine would ideally induce protective immunity prior to sexual debut. Children develop broadly neutralizing antibody (bnAb) responses faster and at higher frequencies than adults, but little is known about the underlying mechanisms or the potential role of Fc-mediated effector f...

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Dades bibliogràfiques
Publicat a:mSphere
Autors principals: Muenchhoff, M., Chung, A. W., Roider, J., Dugast, Anne-Sophie, Richardson, Simone, Kløverpris, Henrik, Leslie, Alasdair, Ndung’u, Thumbi, Moore, Penny, Alter, Galit, Goulder, Philip J. R.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7763548/
https://ncbi.nlm.nih.gov/pubmed/33361123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mSphere.00880-20
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