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Implications of Metastable Nicks and Nicked Holliday Junctions in Processing Joint Molecules in Mitosis and Meiosis

Joint molecules (JMs) are intermediates of homologous recombination (HR). JMs rejoin sister or homolog chromosomes and must be removed timely to allow segregation in anaphase. Current models pinpoint Holliday junctions (HJs) as a central JM. The canonical HJ (cHJ) is a four-way DNA that needs specia...

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Detalhes bibliográficos
Publicado no:Genes (Basel)
Autor principal: Machín, Félix
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7763299/
https://ncbi.nlm.nih.gov/pubmed/33322845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes11121498
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