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Stretching DNA origami: effect of nicks and Holliday junctions on the axial stiffness

The axial stiffness of DNA origami is determined as a function of key nanostructural characteristics. Different constructs of two-helix nanobeams with specified densities of nicks and Holliday junctions are synthesized and stretched by fluid flow. Implementing single particle tracking to extract for...

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Dettagli Bibliografici
Pubblicato in:Nucleic Acids Res
Autori principali: Jung, Wei-Hung, Chen, Enze, Veneziano, Remi, Gaitanaros, Stavros, Chen, Yun
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7708044/
https://ncbi.nlm.nih.gov/pubmed/33152066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa985
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