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Implications of Metastable Nicks and Nicked Holliday Junctions in Processing Joint Molecules in Mitosis and Meiosis

Joint molecules (JMs) are intermediates of homologous recombination (HR). JMs rejoin sister or homolog chromosomes and must be removed timely to allow segregation in anaphase. Current models pinpoint Holliday junctions (HJs) as a central JM. The canonical HJ (cHJ) is a four-way DNA that needs specia...

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Bibliografiske detaljer
Udgivet i:Genes (Basel)
Hovedforfatter: Machín, Félix
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7763299/
https://ncbi.nlm.nih.gov/pubmed/33322845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes11121498
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