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Galeon: A Biologically Active Molecule with In Silico Metabolite Prediction, In Vitro Metabolic Profiling in Rat Liver Microsomes, and In Silico Binding Mechanisms with CYP450 Isoforms

Galeon, a natural cyclic-diarylheptanoid (CDH), which was first isolated from Myrica gale L., is known to have potent cytotoxicity against A549 cell lines, anti-tubercular activity against Mycobacterium tuberculosis H37Rv, chemo-preventive potential, and moderate topoisomerase inhibitory activity. H...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Rahman, A. F. M. Motiur, Yin, Wencui, Kadi, Adnan A., Jahng, Yurngdong
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7763192/
https://ncbi.nlm.nih.gov/pubmed/33322201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25245903
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