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SoupX removes ambient RNA contamination from droplet-based single-cell RNA sequencing data
BACKGROUND: Droplet-based single-cell RNA sequence analyses assume that all acquired RNAs are endogenous to cells. However, any cell-free RNAs contained within the input solution are also captured by these assays. This sequencing of cell-free RNA constitutes a background contamination that confounds...
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| Publicado no: | Gigascience |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7763177/ https://ncbi.nlm.nih.gov/pubmed/33367645 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gigascience/giaa151 |
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