N-acetylglucosamine drives myelination by triggering oligodendrocyte precursor cell differentiation

Myelination plays an important role in cognitive development and in demyelinating diseases like multiple sclerosis (MS), where failure of remyelination promotes permanent neuro-axonal damage. Modification of cell surface receptors with branched N-glycans coordinates cell growth and differentiation b...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Sy, Michael, Brandt, Alexander U., Lee, Sung-Uk, Newton, Barbara L., Pawling, Judy, Golzar, Autreen, Rahman, Anas M. A., Yu, Zhaoxia, Cooper, Graham, Scheel, Michael, Paul, Friedemann, Dennis, James W., Demetriou, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2020
Assuntos:
Glycobiology and Extracellular Matrices
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7762951/
https://ncbi.nlm.nih.gov/pubmed/33453988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.015595
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