N-acetylglucosamine drives myelination by triggering oligodendrocyte precursor cell differentiation

Myelination plays an important role in cognitive development and in demyelinating diseases like multiple sclerosis (MS), where failure of remyelination promotes permanent neuro-axonal damage. Modification of cell surface receptors with branched N-glycans coordinates cell growth and differentiation b...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Biol Chem
Prif Awduron: Sy, Michael, Brandt, Alexander U., Lee, Sung-Uk, Newton, Barbara L., Pawling, Judy, Golzar, Autreen, Rahman, Anas M. A., Yu, Zhaoxia, Cooper, Graham, Scheel, Michael, Paul, Friedemann, Dennis, James W., Demetriou, Michael
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2020
Pynciau:
Glycobiology and Extracellular Matrices
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7762951/
https://ncbi.nlm.nih.gov/pubmed/33453988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.015595
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