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N-Acetylglucosamine Inhibits T-helper 1 (Th1)/T-helper 17 (Th17) Cell Responses and Treats Experimental Autoimmune Encephalomyelitis

Current treatments and emerging oral therapies for multiple sclerosis (MS) are limited by effectiveness, cost, and/or toxicity. Genetic and environmental factors that alter the branching of Asn (N)-linked glycans result in T cell hyperactivity, promote spontaneous inflammatory demyelination and neur...

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Bibliografische gegevens
Hoofdauteurs: Grigorian, Ani, Araujo, Lindsey, Naidu, Nandita N., Place, Dylan J., Choudhury, Biswa, Demetriou, Michael
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2011
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3220534/
https://ncbi.nlm.nih.gov/pubmed/21965673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.277814
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