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Mycobacterium tuberculosis infection up-regulates MFN2 expression to promote NLRP3 inflammasome formation
Tuberculosis (TB), caused by the infection of Mycobacterium tuberculosis (MTB), is one of the leading causes of death worldwide, especially in children. However, the mechanisms by which MTB infects its cellular host, activates an immune response, and triggers inflammation remain unknown. Mitochondri...
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| Pubblicato in: | J Biol Chem |
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| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Biochemistry and Molecular Biology
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7762945/ https://ncbi.nlm.nih.gov/pubmed/33454007 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.014077 |
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