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Mycobacterium tuberculosis infection up-regulates MFN2 expression to promote NLRP3 inflammasome formation

Tuberculosis (TB), caused by the infection of Mycobacterium tuberculosis (MTB), is one of the leading causes of death worldwide, especially in children. However, the mechanisms by which MTB infects its cellular host, activates an immune response, and triggers inflammation remain unknown. Mitochondri...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Xu, Fang, Qi, Hui, Li, Jieqiong, Sun, Lin, Gong, Juanjuan, Chen, Yuanying, Shen, Adong, Li, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7762945/
https://ncbi.nlm.nih.gov/pubmed/33454007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.014077
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