Structural and Biochemical Features of Eimeria tenella Dihydroorotate Dehydrogenase, a Potential Drug Target

Dihydroorotate dehydrogenase (DHODH) is a mitochondrial monotopic membrane protein that plays an essential role in the pyrimidine de novo biosynthesis and electron transport chain pathways. In Eimeria tenella, an intracellular apicomplexan parasite that causes the most severe form of chicken coccidi...

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Detalhes bibliográficos
Publicado no:Genes (Basel)
Main Authors: Sato, Dan, Hartuti, Endah Dwi, Inaoka, Daniel Ken, Sakura, Takaya, Amalia, Eri, Nagahama, Madoka, Yoshioka, Yukina, Tsuji, Naotoshi, Nozaki, Tomoyoshi, Kita, Kiyoshi, Harada, Shigeharu, Matsubayashi, Makoto, Shiba, Tomoo
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7762340/
https://ncbi.nlm.nih.gov/pubmed/33297567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes11121468
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