Intramuscular and Intradermal Electroporation of HIV-1 PENNVAX-GP(®) DNA Vaccine and IL-12 Is Safe, Tolerable, Acceptable in Healthy Adults

Background: Several techniques are under investigation to improve the immunogenicity of HIV-1 DNA vaccine candidates. DNA vaccines are advantageous due to their ease of design, expression of multiple antigens, and safety. Methods: The HVTN 098 trial assessed the PENNVAX(®)-GP DNA vaccine (encoding H...

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Publicado no:Vaccines (Basel)
Main Authors: Edupuganti, Srilatha, C. De Rosa, Stephen, Elizaga, Marnie, Lu, Yiwen, Han, Xue, Huang, Yunda, Swann, Edith, Polakowski, Laura, A. Kalams, Spyros, Keefer, Michael, Maenza, Janine, C. Wise, Megan, Yan, Jian, Morrow, Matthew P., Khan, Amir S., Boyer, Jean D., Humeau, Laurent, White, Scott, Sardesai, Niranjan Y., Bagarazzi, Mark L., Gilbert, Peter B., Kublin, James G., Corey, Lawrence, Weiner, David B.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7762306/
https://ncbi.nlm.nih.gov/pubmed/33297341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/vaccines8040741
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