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Three-Dimensional Spheroids as In Vitro Preclinical Models for Cancer Research

Most cancer biologists still rely on conventional two-dimensional (2D) monolayer culture techniques to test in vitro anti-tumor drugs prior to in vivo testing. However, the vast majority of promising preclinical drugs have no or weak efficacy in real patients with tumors, thereby delaying the discov...

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Detalhes bibliográficos
Publicado no:Pharmaceutics
Main Authors: Pinto, Bárbara, Henriques, Ana C., Silva, Patrícia M. A., Bousbaa, Hassan
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7762220/
https://ncbi.nlm.nih.gov/pubmed/33291351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics12121186
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