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Three-Dimensional Culture Systems in Cancer Research: Focus on Tumor Spheroid Model

Cancer cells propagated in three-dimensional (3D) culture systems exhibit physiologically relevant cell-cell and cell-matrix interactions, gene expression and signaling pathway profiles, heterogeneity and structural complexity that reflect in vivo tumors. In recent years, development of various 3D m...

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Detalhes bibliográficos
Publicado no:Pharmacol Ther
Main Authors: Nath, Sritama, Devi, Gayathri R
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4961208/
https://ncbi.nlm.nih.gov/pubmed/27063403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pharmthera.2016.03.013
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