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Enhancing the Low Oral Bioavailability of Sulpiride via Fast Orally Disintegrating Tablets: Formulation, Optimization and In Vivo Characterization
Sulpiride (SUL) is a dopamine D(2)-receptor antagonist used for management of GIT disturbance and it has anti-psychotic activities based on the administered dose. SUL undergoes P-glycoprotein efflux, which lead to poor bioavailability and erratic absorption. Therefore, the objective of this research...
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| 發表在: | Pharmaceuticals (Basel) |
|---|---|
| Main Authors: | , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
MDPI
2020
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7762047/ https://ncbi.nlm.nih.gov/pubmed/33291402 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph13120446 |
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