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Formulation Design and Optimization of Fast Disintegrating Lorazepam Tablets by Effervescent Method

Fast disintegrating tablets of lorazepam were prepared by effervescent method with a view to enhance patient compliance. A 3(2) full factorial design was applied to investigate the combined effect of two formulation variables: amount of crospovidone and mixture of sodium bicarbonate, citric acid and...

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Main Authors: Shirsand, S. B., Suresh, Sarasija, Jodhana, L. S., Swamy, P. V.
Formato: Artigo
Idioma:Inglês
Publicado: Medknow Publications 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3013557/
https://ncbi.nlm.nih.gov/pubmed/21218052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/0250-474X.73911
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