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Hypoxia Dictates Metabolic Rewiring of Tumors: Implications for Chemoresistance
Hypoxia is a condition commonly observed in the core of solid tumors. The hypoxia-inducible factors (HIF) act as hypoxia sensors that orchestrate a coordinated response increasing the pro-survival and pro-invasive phenotype of cancer cells, and determine a broad metabolic rewiring. These events favo...
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| Pubblicato in: | Cells |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
MDPI
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7761956/ https://ncbi.nlm.nih.gov/pubmed/33291643 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9122598 |
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