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P-glycoprotein-mediated chemoresistance is reversed by carbonic anhydrase XII inhibitors
Carbonic anhydrase XII (CAXII) is a membrane enzyme that maintains pH homeostasis and sustains optimum P-glycoprotein (Pgp) efflux activity in cancer cells. Here, we investigated a panel of eight CAXII inhibitors (compounds 1–8), for their potential to reverse Pgp mediated tumor cell chemoresistance...
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| Опубликовано в: : | Oncotarget |
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| Главные авторы: | , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Impact Journals LLC
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5349880/ https://ncbi.nlm.nih.gov/pubmed/27811376 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13040 |
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