ABCA1/ABCB1 Ratio Determines Chemo- and Immune-Sensitivity in Human Osteosarcoma

The ATP Binding Cassette transporter B1 (ABCB1) induces chemoresistance in osteosarcoma, because it effluxes doxorubicin, reducing the intracellular accumulation, toxicity, and immunogenic cell death induced by the drug. The ATP Binding Cassette transporter A1 (ABCA1) effluxes isopentenyl pyrophosph...

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發表在:Cells
Main Authors: Belisario, Dimas Carolina, Akman, Muhlis, Godel, Martina, Campani, Virginia, Patrizio, Maria Pia, Scotti, Lorena, Hattinger, Claudia Maria, De Rosa, Giuseppe, Donadelli, Massimo, Serra, Massimo, Kopecka, Joanna, Riganti, Chiara
格式: Artigo
語言:Inglês
出版: MDPI 2020
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7140509/
https://ncbi.nlm.nih.gov/pubmed/32155954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9030647
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