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Growth Hormone Upregulates Mediators of Melanoma Drug Efflux and Epithelial-to-Mesenchymal Transition In Vitro and In Vivo

SIMPLE SUMMARY: Growth hormone (GH) action is strongly implicated in the progression and therapy resistance in several types of solid tumors which overexpress the GH receptor (GHR). The aim of our study was to characterize the effects of GH and its downstream effector insulin-like growth factor 1 (I...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Cancers (Basel)
Main Authors: Qian, Yanrong, Basu, Reetobrata, Mathes, Samuel C., Arnett, Nathan A., Duran-Ortiz, Silvana, Funk, Kevin R., Brittain, Alison L., Kulkarni, Prateek, Terry, Joseph C., Davis, Emily, Singerman, Jordyn T., Henry, Brooke E., List, Edward O., Berryman, Darlene E., Kopchick, John J.
פורמט: Artigo
שפה:Inglês
יצא לאור: MDPI 2020
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC7761932/
https://ncbi.nlm.nih.gov/pubmed/33291663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12123640
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