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SAT-181 Characterization of Adult Growth Hormone Receptor Gene-Disrupted Mice
Reduced growth hormone (GH) action can extend life- and health-span. Mice with a disrupted GHR gene since birth are dwarf and obese with low levels of IGF-1 and insulin; high levels of GH; and hold the record for the longest-lived laboratory mouse. They are also somewhat resistant to several age-rel...
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| Publicado no: | J Endocr Soc |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Endocrine Society
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6552003/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/js.2019-SAT-181 |
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