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Differential gene signature in adipose tissue depots of growth hormone transgenic mice

Bovine growth hormone transgenic (bGH) mice mimic the clinical condition of acromegaly, having high circulating growth hormone (GH) levels. These mice are giant, have decreased adipose tissue (AT) mass, impaired glucose metabolism, and shortened lifespan. The detrimental effects of excess GH have be...

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Bibliographic Details
Published in:J Neuroendocrinol
Main Authors: Duran-Ortiz, Silvana, Young, Jonathan A., Jara, Adam, Jensen, Elizabeth A., Basu, Reetobrata, List, Edward O., Qian, Yanrong, Kopchick, John J., Berryman, Darlene E.
Format: Artigo
Language:Inglês
Published: 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7606825/
https://ncbi.nlm.nih.gov/pubmed/33043505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jne.12893
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