Development of Sensitive Droplet Digital PCR Assays for Detecting Urinary TERT Promoter Mutations as Non-Invasive Biomarkers for Detection of Urothelial Cancer

SIMPLE SUMMARY: The gold standard method for the diagnosis of bladder cancer (BC) is the invasive and expensive cystoscopy. Telomerase reverse transcriptase (TERT) promoter mutations occur frequently (60–90%) in BC. In this study, we developed highly sensitive droplet digital PCR (ddPCR) assays for...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Hosen, Md Ismail, Forey, Nathalie, Durand, Geoffroy, Voegele, Catherine, Bilici, Selin, Avogbe, Patrice Hodonou, Delhomme, Tiffany Myriam, Foll, Matthieu, Manel, Arnaud, Vian, Emmanuel, Meziani, Sonia, De Tilly, Berengere, Polo, Gilles, Lole, Olesia, Francois, Pauline, Boureille, Antoine, Pisarev, Eduard, Salas, Andrei R. O. S. E., Monteiro-Reis, Sara, Henrique, Rui, Byrnes, Graham, Jeronimo, Carmen, Scelo, Ghislaine, McKay, James D., Calvez-Kelm, Florence Le, Zvereva, Maria
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7761513/
https://ncbi.nlm.nih.gov/pubmed/33260905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12123541
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