Development of Sensitive Droplet Digital PCR Assays for Detecting Urinary TERT Promoter Mutations as Non-Invasive Biomarkers for Detection of Urothelial Cancer

SIMPLE SUMMARY: The gold standard method for the diagnosis of bladder cancer (BC) is the invasive and expensive cystoscopy. Telomerase reverse transcriptase (TERT) promoter mutations occur frequently (60–90%) in BC. In this study, we developed highly sensitive droplet digital PCR (ddPCR) assays for...

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Publicado en:Cancers (Basel)
Main Authors: Hosen, Md Ismail, Forey, Nathalie, Durand, Geoffroy, Voegele, Catherine, Bilici, Selin, Avogbe, Patrice Hodonou, Delhomme, Tiffany Myriam, Foll, Matthieu, Manel, Arnaud, Vian, Emmanuel, Meziani, Sonia, De Tilly, Berengere, Polo, Gilles, Lole, Olesia, Francois, Pauline, Boureille, Antoine, Pisarev, Eduard, Salas, Andrei R. O. S. E., Monteiro-Reis, Sara, Henrique, Rui, Byrnes, Graham, Jeronimo, Carmen, Scelo, Ghislaine, McKay, James D., Calvez-Kelm, Florence Le, Zvereva, Maria
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2020
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7761513/
https://ncbi.nlm.nih.gov/pubmed/33260905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12123541
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