Optimization of Liposomes for Antigen Targeting to Splenic CD169(+) Macrophages

Despite promising progress in cancer vaccination, therapeutic effectiveness is often insufficient. Cancer vaccine effectiveness could be enhanced by targeting vaccine antigens to antigen-presenting cells, thereby increasing T-cell activation. CD169-expressing splenic macrophages efficiently capture...

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Détails bibliographiques
Publié dans:Pharmaceutics
Auteurs principaux: Nijen Twilhaar, Maarten K., Czentner, Lucas, Grabowska, Joanna, Affandi, Alsya J., Lau, Chun Yin Jerry, Olesek, Katarzyna, Kalay, Hakan, van Nostrum, Cornelus F., van Kooyk, Yvette, Storm, Gert, den Haan, Joke M.M.
Format: Artigo
Langue:Inglês
Publié: MDPI 2020
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7760819/
https://ncbi.nlm.nih.gov/pubmed/33255564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics12121138
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