Optimization of Liposomes for Antigen Targeting to Splenic CD169(+) Macrophages

Despite promising progress in cancer vaccination, therapeutic effectiveness is often insufficient. Cancer vaccine effectiveness could be enhanced by targeting vaccine antigens to antigen-presenting cells, thereby increasing T-cell activation. CD169-expressing splenic macrophages efficiently capture...

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Detalhes bibliográficos
Publicado no:Pharmaceutics
Main Authors: Nijen Twilhaar, Maarten K., Czentner, Lucas, Grabowska, Joanna, Affandi, Alsya J., Lau, Chun Yin Jerry, Olesek, Katarzyna, Kalay, Hakan, van Nostrum, Cornelus F., van Kooyk, Yvette, Storm, Gert, den Haan, Joke M.M.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7760819/
https://ncbi.nlm.nih.gov/pubmed/33255564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics12121138
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