Exploiting GRK2 Inhibition as a Therapeutic Option in Experimental Cancer Treatment: Role of p53-Induced Mitochondrial Apoptosis

SIMPLE SUMMARY: The involvement of GRK2 in cancer growth and an inverse correlation with p53 levels were suggested in breast cancer. Furthermore, increased GRK2 expression and activity were detected in thyroid cancer, but its effects and mechanisms of action were not investigated yet. This study aim...

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Bibliographic Details
Published in:Cancers (Basel)
Main Authors: Gambardella, Jessica, Fiordelisi, Antonella, Santulli, Gaetano, Ciccarelli, Michele, Cerasuolo, Federica Andrea, Sala, Marina, Sommella, Eduardo, Campiglia, Pietro, Illario, Maddalena, Iaccarino, Guido, Sorriento, Daniela
Format: Artigo
Language:Inglês
Published: MDPI 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7760517/
https://ncbi.nlm.nih.gov/pubmed/33256128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12123530
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