The Amino-Terminal Domain of GRK5 Inhibits Cardiac Hypertrophy through the Regulation of Calcium-Calmodulin Dependent Transcription Factors

We have recently demonstrated that the amino-terminal domain of G protein coupled receptor kinase (GRK) type 5, (GRK5-NT) inhibits NFκB activity in cardiac cells leading to a significant amelioration of LVH. Since GRK5-NT is known to bind calmodulin, this study aimed to evaluate the functional role...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:Int J Mol Sci
Huvudupphovsmän: Sorriento, Daniela, Santulli, Gaetano, Ciccarelli, Michele, Maione, Angela Serena, Illario, Maddalena, Trimarco, Bruno, Iaccarino, Guido
Materialtyp: Artigo
Språk:Inglês
Publicerad: MDPI 2018
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5877722/
https://ncbi.nlm.nih.gov/pubmed/29543709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19030861
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk