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Exploiting GRK2 Inhibition as a Therapeutic Option in Experimental Cancer Treatment: Role of p53-Induced Mitochondrial Apoptosis

SIMPLE SUMMARY: The involvement of GRK2 in cancer growth and an inverse correlation with p53 levels were suggested in breast cancer. Furthermore, increased GRK2 expression and activity were detected in thyroid cancer, but its effects and mechanisms of action were not investigated yet. This study aim...

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書誌詳細
出版年:Cancers (Basel)
主要な著者: Gambardella, Jessica, Fiordelisi, Antonella, Santulli, Gaetano, Ciccarelli, Michele, Cerasuolo, Federica Andrea, Sala, Marina, Sommella, Eduardo, Campiglia, Pietro, Illario, Maddalena, Iaccarino, Guido, Sorriento, Daniela
フォーマット: Artigo
言語:Inglês
出版事項: MDPI 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7760517/
https://ncbi.nlm.nih.gov/pubmed/33256128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12123530
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