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Receptor Binding Domains of TcdB from Clostridioides difficile for Chondroitin Sulfate Proteoglycan-4 and Frizzled Proteins Are Functionally Independent and Additive

Toxin B (TcdB) produced by Clostridioides difficile is a main pathogenicity factor that affects a variety of different cell types within the colonic mucosa. TcdB is known to utilize frizzled-1,2,7 and chondroitin sulfate proteoglycan-4 (CSPG4) as protein receptors. By using human cervical cancer cel...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Toxins (Basel)
Egile Nagusiak: Henkel, Daniel, Tatge, Helma, Schöttelndreier, Dennis, Tao, Liang, Dong, Min, Gerhard, Ralf
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: MDPI 2020
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7759879/
https://ncbi.nlm.nih.gov/pubmed/33255261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins12120736
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