The Conserved Cys-2232 in Clostridioides difficile Toxin B Modulates Receptor Binding

Clostridioides difficile toxins TcdA and TcdB are large clostridial glucosyltransferases which are the main pathogenicity factors in C. difficile-associated diseases. Four highly conserved cysteines are present in all large clostridial glucosyltransferases. In this study we focused on the conserved...

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Detalhes bibliográficos
Publicado no:Front Microbiol
Main Authors: Chung, Soo-Young, Schöttelndreier, Dennis, Tatge, Helma, Fühner, Viola, Hust, Michael, Beer, Lara-Antonia, Gerhard, Ralf
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6212469/
https://ncbi.nlm.nih.gov/pubmed/30416488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2018.02314
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