Hepatic Tumor Cell Morphology Plasticity under Physical Constraints in 3D Cultures Driven by YAP–mTOR Axis

Recent studies undoubtedly show that the mammalian target of rapamycin (mTOR) and the Hippo–Yes-associated protein 1 (YAP) pathways are important mediators of mechanical cues. The crosstalk between these pathways as well as de-regulation of their signaling has been implicated in multiple tumor types...

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Detalhes bibliográficos
Publicado no:Pharmaceuticals (Basel)
Main Authors: Frtús, Adam, Smolková, Barbora, Uzhytchak, Mariia, Lunova, Mariia, Jirsa, Milan, Hof, Martin, Jurkiewicz, Piotr, Lozinsky, Vladimir I., Wolfová, Lucie, Petrenko, Yuriy, Kubinová, Šárka, Dejneka, Alexandr, Lunov, Oleg
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7759829/
https://ncbi.nlm.nih.gov/pubmed/33260691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph13120430
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