Targeting the mTOR Signaling Pathway Utilizing Nanoparticles: A Critical Overview

Proteins of the mammalian target of rapamycin (mTOR) signaling axis are overexpressed or mutated in cancers. However, clinical inhibition of mTOR signaling as a therapeutic strategy in oncology shows rather limited progress. Nanoparticle-based mTOR targeted therapy proposes an attractive therapeutic...

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Bibliographic Details
Published in:Cancers (Basel)
Main Authors: Lunova, Mariia, Smolková, Barbora, Lynnyk, Anna, Uzhytchak, Mariia, Jirsa, Milan, Kubinová, Šárka, Dejneka, Alexandr, Lunov, Oleg
Format: Artigo
Language:Inglês
Published: MDPI 2019
Subjects:
Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6356373/
https://ncbi.nlm.nih.gov/pubmed/30642006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11010082
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